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Pigmented lesions are caused by a proliferation of melanocytes in the skin. Melanocytes are the cells that manufacture melanin, which is the dark pigment in skin. Most of us have some form of pigmented lesion. They include brown age spots (lentigines), freckles (ephileds), and moles (nevi). Lesions without color are called non-pigmented lesions. They include warts and skin tags